教育经历
- 2000-2004，taptap点点投注，药学院，工学，学士
- 2004-2007，taptap点点投注，药学院，医学，硕士
- 2012-2016，taptap点点投注，taptap点点app官方网站，工学，博士
工作经历
- 2007-2009，taptap点点投注药学院，研究实习员
- 2010-2014，taptap点点投注药学院，助理研究员
- 2015-2016，taptap下载ios游戏，助理研究员
- 2017-至今，taptap下载ios游戏，副研究员
研究内容
- 食品功能胶体及功能因子稳态化研究
- 食品功能因子的健康效应及营养干预机制研究
- 食品加工污染物的毒性作用及机制研究
承担项目
- 国家自然科学基金面上项目：玉米醇溶蛋白/酪蛋白酸钠/果胶复合颗粒的可控构建及其用于食品营养递送体系的研究（项目批准号：31871799），2019.1-2020.12，项目负责人
- 国家自然科学基金青年项目：基于可食用蛋白/壳聚糖盐自组装构建姜黄素结肠释放载运体系的研究（项目批准号：31501479），2016.1-2018.12，项目负责人
- “十三五”国家重点研发计划：风险因子与代谢标志物表征研究（课题编号：2017YFC1600505），2018.1-2021.12，子课题负责人
- 农业部公益性行业项目子课题：未知毒物的早期检测技术研究（课题编号：201203069-1），2012.1-2016.12，子课题负责人
- 金龙鱼创新基金项目：油脂中矿物油的分析方法开发及毒理学评价，2022.1-2025.1，项目负责人
- 北京食品营养与人类健康高精尖创新中心开放基金项目：3-氯丙醇酯的体内吸收、分布、代谢以及潜在的致毒代谢物研究，2017.1-2019.12，项目负责人
- 中加食品营养与健康联合实验室开放基金项目：玉米醇溶蛋白/酪蛋白酸钠/果胶复合颗粒的可控构建及其用于谷物营养成分递送体系的研究，2020.7-2022.6，项目负责人.
- 企业委托横向项目：类母乳脂产品在SD大鼠体内的营养学研究，2021.5-2021.12，项目负责人
- 企业委托横向项目：Sn-2棕榈酸对大鼠钙吸收和脂肪吸收的影响及其机制研究，2017.1-2017.12，项目负责人
- 企业委托横向项目：粮油制品质量控制与功能化技术研究，2015.4-2016.3，项目负责人
- “十四五”国家重点研发计划：提升儿童视力的营养功能因子挖掘与零食化膳食补充剂创制（课题编号：2023YFF1104304），子课题负责人
论文
- Wenwen Liu, Lin Zhu, Yongjia Liu, Zhuohong Xie, Puyu Yang, Yaqiong Zhang*, Boyan Gao, Liangli (Lucy) Yu, Laccase and glucono-δ-lactone dual-induced gelation of casein and arabinoxylan: microstructures, physicochemical properties, and pH-responsive release behavior, Food Hydrocolloids (IF11.504), 2023,135,108235 (JCR一区)
- Jiaping Liu, Yaqiong Zhang*, Wenwen Liu, Boyan Gao and Liangli (Lucy) Yu, A novel zein-based composite nanoparticles for improving bioaccessibility and anti-inflammatory activity of resveratrol, Foods (IF5.561), 2021, 10, 2773 (JCR一区)
- Yali Huang#, Ning Yang#, Yaqiong Zhang#, Jingwen Hou, Yadong Gao, Liu Tian, Zhu Jin, Yuanyuan Shen*, Shengrong Guo*, The gelling behavior of gellan in the presence of different sodium salts, International Journal of Biological Macromolecules (IF8.025), 2021, 193, 768-777 (JCR一区)
- Yanfang Li, Ming Li, Jiaping Liu, Wenhao Zheng, Yaqiong Zhang*, Tongcheng Xu, Boyan Gao, Liangli (Lucy) Yu, Chemical composition profiling and biological activities of phenolic compounds in eleven red sorghums, Journal of Agricultural and Food Chemistry (IF5.895), 2021, 69, 9407-9418. (JCR一区)
- Jiaping Liu, Bo Wang, Xiaowei Zhang, Yaqiong Zhang*, Liangli (Lucy) Yu. Effect of gypenosides diet intervention on obesity control and gut microbiota regulation in mice, Journal of Chinese Institute of Food Science and Technology (in Chinese), 2022.
- Puyu Yang#, Yaqiong Zhang#, Yanfang Li, Michael Granvogl, Boyan Gao,* Liangli Lucy Yu, Proteomic analyses of 3-monochloropropanediol 1-monooleate and 1-monostearate induced testicular toxicity in a 90-day Sprague-Dawley rats’ study, Journal of Agricultural and Food Chemistry (IF5.895), 2021, 69, 4542-4549. (JCR一区)
- Jiaping Liu, Yaqiong Zhang*, Songzhe He, Aimei Zhou, Boyan Gao, Mengyu Yan, Liangli (Lucy) Yu, Microbial transglutaminase-induced cross-linking of sodium caseinate as the coating stabilizer of zein nanoparticles, LWT (IF6.056), 2021, 138, 110624. (JCR一区)
- Ming Li, Tongcheng Xu, Wenhao Zheng, Boyan Gao, Hongyan Zhu, Ruofei Xu, Hanyu Deng, Bo Wang, Yanbei Wu, Xiangjun Sun, Yaqiong Zhang*, Liangli (Lucy) Yu, Triacylglycerols compositions, soluble and bound phenolics of red sorghums, and their radical scavenging and anti-inflammatory activities, Food Chemistry (IF9.231), 2021, 340, 128123. (JCR一区)
- Boyan Gao, Mengchu Jin, Wenhao Zheng, Yaqiong Zhang*, Liangli (Lucy) Yu. Current progresses on MCPD esters in 2018-2019 and their future research trends, Journal of Agricultural and Food Chemistry (IF5.895), 2020, 68, 12984-12992. (JCR一区)
- Bo Wang, Ming Li, Hang Gao, Xiangjun Sun, Boyan Gao, Yaqiong Zhang*, Liangli (Lucy) Yu, Chemical composition of tetraploid Gynostemma pentaphyllum gypenosides and their suppression on inflammatory response by NF-κB/MAPKs/AP-1 signaling pathways, Food Science & Nutrition (IF3.553), 2020, 8, 1197-1207. (JCR二区)
- Lijuan Du, Weiying Lu, Yaqiong Zhang*, Boyan Gao*, Liangli (Lucy) Yu, Detection of milk powder in liquid whole milk using hydrolyzed peptide and intact protein mass spectral fingerprints coupled with data fusion technologies, Food Science & Nutrition (IF3.553), 2020, 8, 1471-1479. (JCR二区)
- Yaqiong Zhang, Bo Wang, Yan Wu, Boyan Gao, Liangli (Lucy) Yu, Fabrication and characterization of zein composite particles coated by caseinate-pectin electrostatic complexes with improved structural stability in acidic aqueous environments, Molecules (IF4.927), 2019, 24, 2535. (JCR二区)
- Yaqiong Zhang, Ming Li, Hang Gao, Bo Wang, Tongcheng Xu*, Boyan Gao*, Liangli (Lucy) Yu, Triacylglycerol, fatty acid, and phytochemical profiles in a new red sorghum variety (Ji Liang No. 1) and its antioxidant and anti‐inflammatory properties, Food Science & Nutrition (IF3.553), 2019, 7, 949-958. (JCR二区)
- Yinghua Luo#, Yaqiong Zhang#, Fanghao Yuan, Boyan Gao, Ziyuan Wang, Liangli (Lucy) Yu. Triacylglycerols composition analysis of olive oils by ultra-performance convergence chromatography combined with quadrupole time-of-flight mass spectrometry, International Journal of Food Science and Technology (IF3.612), 2018, 54, 871-879. (JCR二区)
- Fangyi Yao, Yaqiong Zhang*, Liangli (Lucy) Yu. The effect of caseinate derivatives on the redispersibility and storage stability of freeze-dried zein nanoparticles, Journal of Chinese Institute of Food Science and Technology (in Chinese), 2018, 18 (11): 152-158.
- Jinli Xue, Yaqiong Zhang*, Guoren Huang, Jie Liu, Margaret Slavin, Liangli (Lucy) Yu. Zein-caseinate composite nanoparticles for bioactive delivery using curcumin as a probe compound, Food Hydrocolloids (IF11.504) , 2018, 83, 25-35. (JCR一区)
- Yaqiong Zhang, Fangyi Yao, Jie Liu, Wen Zhou, Liangli (Lucy) Yu*, Synthesis and characterization of alkylated caseinate, and its structure-curcumin loading property relationship in water, Food Chemistry (IF9.231), 2018, 244:246-253. (JCR一区)
- Yaqiong Zhang, Puyu Yang, Fangyi Yao, Jie Liu, Liangli (Lucy) Yu*, Grafting C8-C16 alkyl groups altered the self-assembly and curcumin-loading properties of sodium caseinate in water, Data in Brief, 2018, 16, 276-285.
- Puyu Yang, Hong Zhang, Junchen Liu, Jinyu Hu, Jianchun Wan, Yaqiong Zhang*, Liangli Yu*, Review of Sn-2 palmitate implications for infant health, Journal of Food Science and Technology (invited, in Chinese), 2018, 36(4): 41-45.
- Jianchun Wan, Songyou Hu, Jorg J. Jacoby, Jie Liu, Yaqiong Zhang*, Liangli (Lucy) Yu*, The impact of dietary sn-2 palmitic triacylglycerols in combination with docosahexaenoic acid or arachidonic acid on lipid metabolism and host faecal microbiota composition in Sprague Dawley rats, Food & Function (IF6.317), 2017, 8, 1793-1802. (JCR一区)
- Boyan Gao, Yinghua Luo, Weiying Lu, Jie Liu, Yaqiong Zhang*, Liangli (Lucy) Yu*, Triacylglycerol compositions of sunflower, corn and soybean oils examined with supercritical CO2 ultra-performance convergence chromatography combined with quadrupole time-of-flight mass spectrometry, Food Chemistry (IF9.231), 2017, 218, 569-574. (JCR一区)
- Yue Zhao#, Yaqiong Zhang#, Zhongfei Zhang, Jie Liu, Yi-lin Wang, Boyan Gao, Yuge Niu, Xiangjun Sun, Liangli Yu*, Formation of 3-MCPD fatty acid esters from monostearoyl glycerol and the thermal stability of 3-MCPD monoesters, Journal of Agricultural and Food Chemistry (IF5.895), 2016, 64, 8918-8926. (JCR一区)
- Yaqiong Zhang, Yuge Niu, Fangyi Yao, Bona Dai, Qin Wang, Liangli (Lucy) Yu*, Preparation of novel cross-linked and octylated caseinates using a biphasic enzymatic procedure and their functional properties, Journal of Agricultural and Food Chemistry (IF5.895), 2014, 62(34):8655-8662. (JCR一区)
- Yaqiong Zhang, Yuge Niu, Yangchao Luo, Mei Ge, Tian Yang, Liangli (Lucy) Yu*, Qin Wang, Fabrication, characterization and antimicrobial activities of thymol-loaded zein nanoparticles stabilized by sodium caseinate-chitosan hydrochloride double layers, Food Chemistry (IF9.231), 2014,142:269-275. ESI高影响论文 (JCR一区)
- 1.Yingjie Wang, Shuaizhen Fang, Mingzhe Deng, Liangli (Lucy) Yu, Yaqiong Zhang*, A food-grade arabinoxylan/caseinate hydrogel for sustained delivery of cyanidin-3-glucoside: Temporal optimization of cytoprotection against blue light-induced retinal epithelium injury, International Journal of Biological Macromolecules, 2026, 367, 152602
- 2.Lin Zhu, Mingzhe Deng, Hong Zhang, Zhenbo Xu, Peijin Tong, Jianchun Wan, Boyan Gao, Liangli (Lucy) Yu, Yaqiong Zhang*, Sn-2 palmitate ameliorates dyslipidemia in high-fat-fed aged mice via bile acid-mediated gut-liver-adipose cross-talk, Food Bioscience, 2026, 81, 109136
- 3.Zhang Miao, Wang Chengxu, Zhu Lin, Zhu Hanshu, Zhang Yaqiong, Yu Liangli, Gao Boyan, Integrated transcriptome-metabolome analysis reveals attenuated combined toxicity: Antagonistic interactions of three thermal processing contaminants in murine kidney-urine systems, Food and Chemical Toxicology, 2026, 212,116037
- 4.Lin Zhu, Mingming Zhang, Hong Zhang, Hai Zhang, Boyan Gao, Liangli (Lucy) Yu, Yaqiong Zhang*, Integrated Metabolomics and Proteomics Reveals Gender-Dependent Immunotoxicity Mechanisms of Mineral Oil Saturated Hydrocarbons (MOSH) in F344 Rats, Journal of Agricultural and Food Chemistry, 2025,74(9), 7976–7990
- 5.Lin Zhu, Mingming Zhang, Hong Zhang, Hai Zhang, Boyan Gao, Liangli (Lucy) Yu, Yaqiong Zhang*, The Carbon Number-specific Impact of Mineral Oil Saturated Hydrocarbons on Inducing Colonic Inflammation in Female and Male Fischer 344 Rats, Food Frontiers, 2025, 0, 1-16
- 6.Lin Zhu, En Thong Low, Hong Zhang, Zhenbo Xu, Peijin Tong, Jianchun Wan, Boyan Gao, Liangli (Lucy) Yu, Yaqiong Zhang*, Sn-2 palmitate attenuates neuroinflammation in aged mice via sex-specific modulation of the microbiota-gut-brain axis, Brain, behavior and immunity integrative, 2025,12, 100140
- 7.Zhu, Hanshu; Zhang, Miao; Zhu, Lin; Wang, Chenxu; Zhang, Yaqiong; Yu, Liangli; Gao, Boyan, Formation patterns, in vivo toxic effects and metabolomic conditions of oxidative derivatives of triolein, Journal of Agricultural and Food Chemistry, 2025, 73(32), 20421-20433
- 8.Lee, Ethan; Li, Yanfang; Wu, Xianli; Qin, Jianwei; Zhang, Yaqiong; Gao, Boyan; Slavin, Margaret; He, Xiaohua; Yu, Liangli, Chemical Composition of Coriander (Coriandrum sativum. L) Extract and its Ability in Reducing the Risk of SARS-CoV-2 Infection and Scavenging Radicals, ACS Food Science & Technology, 2025, 5, 2215–2224
- 9.Miao Zhang, Chenxu Wang, Lin Zhu, Hanshu Zhu, Wenhao Zheng, Weiying Lu,Yuge Niu, Yaqiong Zhang, Boyan Gao, * Liangli (Lucy) Yu, Integrated metabolomic and transcriptomic analyses of mouse liver reveals the in vivo toxicity and mechanisms of individual and combined toxicants formed in the thermal processing of high-fat diets, Journal of Agricultural and Food Chemistry, 2024,72 (3), 1603–1614.
- 10.Shuaizhen Fang, Yingjie Wang, Lin Zhu, Yaqiong Zhang*, Liangli (Lucy) Yu, Effect of zein nanoparticles addition on anthocyanin and lutein dual-loaded nanocomposite hydrogels: Structure, physico-chemical and delivery properties, International Journal of Biological Macromolecules, 2025,309,142967
- 11.Wenchen Li, Yunfei Sha, Junwei Xiong, Yumei Chen, Yaqiong Zhang, Jianhao Zhang, Lan Xu，Weiying Lu, LIGHt-based rapid detection of starch in tobacco leaves by smartphone sensing, Scientific Reports, 2025, 15, 6689
- 12.Yaqiong Zhang, Yinghua Luo, Boyan Gao, Liangli Yu, Psyllium: A Nutraceutical and Functional Ingredient in Foods, Annual Review of Food Science and Technology, 2025,16, 355-377
- 13.Lin Zhu, Mingming Zhang, Boyan Gao, Hong Zhang, Hai Zhang, Yaqiong Zhang,* and Liangli Lucy Yu, Subchronic Toxicity of Mineral Oil Saturated Hydrocarbons (MOSH) in Relation to Its Carbon Number Range and Gender of Fischer F344 Rats, Journal of Agricultural and Food Chemistry, 2024,72,22848-22859
- 14.Chenxu Wang, Hanshu Zhu, Miao Zhang, Lin Zhu, Wenhao Zheng, Weiying Lu, Yuge Niu, Yaqiong Zhang, Boyan Gao,* Liangli (Lucy) Yu, Nighty-day sub-chronic toxicology of individual and combined toxicants from thermal processing of lipid-rich foods, Journal of Agricultural and Food Chemistry, 2024, 72(50), 28122-28137
- 15.Lin Zhu, Shuaizhen Fang, Yaqiong Zhang,* Xiangjun Sun, Puyu Yang , Weiying Lu and Liangli Yu, Effects of sn-2 Palmitic Triacylglycerols and the Ratio of OPL to OPO in Human Milk Fat Substitute on Metabolic Regulation in Sprague-Dawley Rats, Nutrients, 2024, 16, 1299
- 16.Huan Wu, Zhihao Liu, Yaqiong Zhang, Boyan Gao, Yanfang Li, Xiaohua He,*, Jianghao Sun, Uyory Choe, Pei Chen, Ryan Blaustein,*, Liangli (Lucy) Yu, Chemical Composition of Turmeric (Curcuma longa L.) Ethanol Extract and Its Antimicrobial Activities and Free Radical Scavenging Capacities, Foods, 2024, 13, 1550
- 17.Shuaizhen Fang, Wenwen Liu, Yaqiong Zhang,* Yanfang Li, Boyan Gao, Puyu Yang, Zhuohong Xie, Liangli (Lucy) Yu, Effect of arabinoxylan amount and molecular structure on the microstructure, physicochemical and delivery properties of casein/arabinoxylan composite hydrogels, Food Hydrocolloids, 2024, 146, 109216
- 18.Boyan Gao , Hanshu Zhu , Zhihao Liu, Xiaohua He, Jianghao Sun, Yanfang Li, Xianli Wu, Pamela Pehrsson, Yaqiong Zhang*, Liangli Yu，Chemical Compositions of Scutellaria baicalensis Georgi.(Huangqin) Extracts and Their Effects on ACE2 Binding of SARS-CoV-2 Spike Protein, ACE2 Activity, and Free Radicals, International Journal of Molecular Science, 2024, 25, 2045
- 19.Boyan Gao,† , Hanshu Zhu,†, Zhihao Liu, Xiaohua He, Jianghao Sun, Yanfang Li, Xianli Wu, Pamela Pehrsson, Yaqiong Zhang*, Yuanhang Yao,* and Liangli Yu, Chemical Compositions of Lianqiao (Forsythia suspensa) Extracts and Their Potential Health Benefits, Pharmaceuticals, 2024, 17,740
- 20.Lin Zhu, Shuaizhen Fang, Hong Zhang, Xiangjun Sun, Puyu Yang, Jianchun Wan, Yaqiong Zhang,* Weiying Lu, Liangli Yu. Total Sn-2 Palmitic Triacylglycerols and the Ratio of OPL to OPO in Human Milk Fat Substitute Modulated Bile Acid Metabolism and Intestinal Microbiota Composition in Rats, Nutrients, 2023, 15, 4929
- 21.Ethan Y. Lee, Zhihao Liu, Yanfang Li, Thomas T.Y. Wang, Jianghao Sun, Xianli Wu, Monica Whent, Pamela Pehrsson, Yaqiong Zhang, Boyan Gao, Yuanhang Yao, * Liangli (Lucy) Yu. The Chemical Constituents of Parsley (Petroselinum crispum) Leaf Extract and Its Potential in Mitigating the Effects of Viral Infections, ACS Food Science & Technology, 2023, 3, 2108-2116
- 22.Yuanhang Yao,* Uyory Choe,* Yanfang Li,* Zhihao Liu, Melody Zeng, Thomas T.Y. Wang, Jianghao Sun, Xianli Wu, Pamela Pehrsson, Xiaohua He, Yaqiong Zhang,# Boyan Gao, Jeffrey C. Moore, Pei Chen, Margaret Slavin,# Liangli (Lucy) Yu, Chemical Composition of Rosemary (Rosmarinus officinalis L.) Extract and Its Inhibitory Effects on SARS-CoV-2 Spike Protein-ACE2 Interaction and ACE2 Activity, and Free Radical Scavenging Capacities, Journal of Agricultural and Food Chemistry, 2023, 71, 18735–18745
- 23.Lin Zhu, Shuaizhen Fang, Wenwen Liu, Hong Zhang, Yaqiong Zhang,* Zhuohong Xie, Puyu Yang, Jianchun Wan, Boyan Gao, Liangli (Lucy) Yu, Triacylglycerol structure and composition of human milk fat substitute modulate bile acid metabolism and gut microbiota in newly-weaned Sprague–Dawley rats, Food & Function, 2023, 14, 7574 - 7585.
- 24.Uyory Choe, Yanfang Li, Zhihao Liu, Yuanhang Yao*, Xiaohua He, Jianghao Sun, Xianli Wu, Pamela Pehrsson, Yaqiong Zhang,* Boyan Gao, Thomas T.Y. Wang, Liangli (Lucy) Yu, Chemical Compositions of Dill (Anethum graveolens L.) Water and Ethanol Extracts and Their Potential in Blocking the SARS-CoV-2 Entry into Cells and Free Radical Scavenging Capacities, ACS Food Science & Technology, 2023, 3, 1654-1662.
- 25.Yaqiong Zhang*, Xin Jia. Delivery systems to enhance bioaccessibility and bioavailability of bioactive factors: structure, property, and food applications, Foods, 2023,12,3127
专利著作
- Liangli (Lucy) Yu, Uyory Choe, Yanfang Li, Yaqiong Zhang. ‘Oils from Fruit, Spice, and Herb Seeds’ In 'Bailey’s Industrial Oil and Fat Products’ (7th edition), John Wiley & Sons Inc., ISBN-13:978-1119257882, ISBN-10:1119257883, Publication Date: May 2020
- Yaqiong Zhang, Hui Huang. ‘Delivery systems to enhance bioavailability and bioaccessibility of active factors’ In ‘Evidence-based Nutraceuticals and Functional Foods’, The Royal Society of Chemistry (RSC), 2023.
- 张亚琼，姚芳懿，一种经改性的蛋白及其制备方法和应用，发明专利，授权号：ZL 201610237860.6
- 张亚琼，姚芳懿，姜黄素复合颗粒及其制备方法和应用，发明专利，授权号：ZL 201510819903.7
- 张亚琼，姚芳懿，一种新的酪蛋白衍生物及其制备方法，发明专利，授权号：ZL 201410312926.4
- 赵越，张亚琼，陆维盈，一种除去3-氯丙二醇酯的方法，发明专利，授权号：ZL 201610392375.6
- 张亚琼，刘嘉平，一种提高醇溶蛋白颗粒稳定性的方法，发明专利，申请号：202110505709.7
- 张亚琼，朱琳，张虹，一种油脂组合物及其应用，发明专利，申请号：202210480584.1
- 张亚琼，朱琳，张虹，有效改善代谢的油脂组合物及其应用，发明专利，申请号：202210481200.8
- 张亚琼，高博彦，李艳芳，一种内源性标志物集合及其用于评估染料木素摄入情况的用途，发明专利，申请号：202210601163X
- 张亚琼，高博彦，李艳芳，一种内源性标志物集合及其用于评估黄豆苷元摄入情况的用途，发明专利，申请号：2022106011644
获奖
- 2021年taptap点点app官方网站第二届教师教学竞赛一等奖
- 2021年taptap点点投注第六届青年教师教学竞赛三等奖
- 2021年度taptap点点app官方网站先进个人
- 2018年度taptap点点投注“金龙鱼青年教师奖”
- 2011年度上海市自然科学奖三等奖1项（第三完成人）
- 2011年度“SMC－taptap点点投注晨星青年学者奖励计划”C等
- 2009年度taptap点点投注药学院“优秀班主任工作奖”
- 2008年度taptap点点投注药学院“工会活动优秀奖”
- 2018-2021年度考核良好，2018-2020年聘期考核优秀